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                             October 3, 2023

       Qiaoling Lu
       Chief Executive Officer
       Sentage Holdings Inc.
       501, Platinum Tower
       233 Taicang Road
       HuangPu, Shanghai City 200001
       People's Republic of China

                                                        Re: Sentage Holdings
Inc.
                                                            Annual Report on
Form 20-F for Fiscal Year Ended December 31, 2022
                                                            Response dated
September 15, 2023
                                                            File No. 001-40580

       Dear Qiaoling Lu:

              We have reviewed your September 15, 2023 response to our comment
letter and have the
       following comments.

              Please respond to this letter within ten business days by
providing the requested
       information or advise us as soon as possible when you will respond. If
you do not believe a
       comment applies to your facts and circumstances, please tell us why in
your response.

              After reviewing your response to this letter, we may have
additional comments. Unless
       we note otherwise, any references to prior comments are to comments in
our August 31,
       2023 letter.

       Form 20-F for Fiscal Year Ended December 31, 2022

       Item 5. Operating and Financial Review and Prospects
       Operating expenses, page 97

   1.                                                   Please refer to prior
comment 12. We note that your proposed disclosure in your response
                                                        is nearly the same as
the existing disclosure on page 97 of your Form 20-F for the year
                                                        ended December 31,
2022. Please revise future filings, and provide us with a draft of your
                                                        proposed disclosure, to
disclose the individual material components which make up your
                                                        total selling, general
and administrative expenses for the reporting periods presented. For
                                                        example, your
disclosure should:
                                                            identify and
quantify each individually significant component of selling, general and
                                                             administrative
expenses;
 Qiaoling Lu
Sentage Holdings Inc.
October 3, 2023
Page 2
                quantify the change in each respective component during each
period; and
                discuss the reasons for the increases or decreases in the
specific dollar amounts for
              each of the components identified.
Consolidated Financial Statements
Note 2     Summary of significant accounting policies
Convenience translation, page F-13

2.       Please refer to prior comment 16. We note in your proposed disclosure
that you perform
         translation for income and expense items using the average exchange
rate for    the next
         financial year.    Please tell us how this policy complies with the
guidance in ASC 830 or,
         if accurate, revise your disclosure to clarify that your translation
of income and expense
         items uses an average exchange rate for the periods presented in the
consolidated financial
         statements. Refer to ASC 830-10-55-10 and 55-11.
General

3.       We note that you responded to prior comments 1, 2, 4 and 7 with a
statement that you will
         make the requested changes in future filings. Provide us with an
example of the
         responsive disclosure to each comment in your response to this comment
letter.
        Please contact Katharine Garrett at 202-551-2332 or William Schroeder
at 202-551-3294
if you have questions regarding comments on the financial statements and
related matters. Please
contact Aisha Adegbuyi at 202-551-8754 or Christian Windsor at 202-551-3419
with any other
questions.



FirstName LastNameQiaoling Lu                                   Sincerely,
Comapany NameSentage Holdings Inc.
                                                                Division of
Corporation Finance
October 3, 2023 Page 2                                          Office of
Finance
FirstName LastName